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metyrapone
PubChem Notes:
Metyrapone An inhibitor of the enzyme STEROID 11 BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
MediLexicon metyrapone - Medical Dictionary Definition for Term 'metyrapone'
[1. An inhibitor of adrenocortical steroid C-11 β-hydroxylation, administered orally or intravenously to determine the ability of the pituitary gland to increase its secretion of corticotropin; because 11-deoxycorticosteroids, as a consequence of metyrapone administration, only weakly inhibit pituitary corticotropin secretion, the normal pituitary gland will appreciably increase its output of this hormone.
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pre_formula( "InChI=1/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3", "jqp073/4174.html" ); ?>
Molecular Formula:
C14H14N2O
InChI: InChI=1/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3
InChIKey: InChIKey=FJLBFSROUSIWMA-UHFFFAOYAJ
SMILES: CC(C)(C1=CC=CN=C1)C(=O)C2=CC=CN=C2
CAS number 54-36-4
Names:
METOPIRONE (TN)
metyrapone
Metyrapone
METYRAPONE
Metyrapone
metyrapone
1-Propanone, 2-methyl-1,2-di-3-pyridinyl-
2-methyl-1,2-dipyridin-3-yl-propan-1-one
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Registries:
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PubChem CID 4174
Beilstein =163023
CAS 54-36-4 (from NIST)
ChEBI 6911
chemPDB MYT
Kegg C07205
Kegg D00410
PubChem ID 10396161
PubChem ID 9414
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