gabexate

Gabexate A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

Molecular Formula: C₁₆H₂₃N₃O₄

InChI: InChI=1/C16H23N3O4/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18/h7-10H,2-6,11H2,1H3,(H4,17,18,19)/f/h17-18H2

InChIKey: InChIKey=YKGYIDJEEQRWQH-LFNRWQDLCR
SMILES: CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N

Names:
    Benzoic acid, 4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxy)-, ethyl ester
    Ethyl p-hydroxybenzoate 6-guanidinohexanoate
    ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate
    Gabexate [INN]
    gabexate
    Gabexato [INN-Spanish]
    Gabexatum [INN-Latin]
    39492-01-8
    56974-61-9

Registries:
    PubChem CID 3447
    PubChem ID 179515