bupropion

[(Science: chemical) a unicyclic, aminoketone antidepressant. The mechanism of its therapeutic actions is not well understood, but it does appear to block dopamine uptake. The compound is metabolised to pharmacologically active plasma metabolites. It is effective in the treatment of major depression and has some beneficial effects in attention-deficit hyperactive children and adults. Its major adverse effect is dose-related seizures in a small number of patients. Pharmacological action: antidepressive agents, second-generation, dopamine uptake inhibitors. chemical name: 1-Propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-

Molecular Formula: C₁₃H₁₈ClNO

InChI: InChI=1/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3

InChIKey: InChIKey=SNPPWIUOZRMYNY-UHFFFAOYAJ
SMILES: CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1

CAS number 34841-39-9

Names:
    Bupropion
    bupropion
    KBio3_001467
    1-(3-chlorophenyl)-2-(tert-butylamino)propan-1-one

Registries:
    PubChem CID 444
    Beilstein =2101062
    CAS 34841-39-9 (from NIST)
    CAS 34911-55-2 (from NIST)
    ChEBI 3219
    Kegg C06860
    PubChem ID 11371567
    PubChem ID 9078