busulfan

[(Science: chemical) An alkylating agent having a selective immunosuppressive effect on bone marrow. It has been used in the palliative treatment of chronic myeloid leukaemia, but although symptomatic relief is provided, no permanent remission is brought about. According to the fourth annual report on carcinogens (ntp 85-002, 1985), busulfan is listed as a known carcinogen. Pharmacological action: alkylating agents, antineoplastic agent, alkylating, carcinogens, immunosuppressive agents. chemical name: 1,4-Butanediol, dimethanesulfonate

Molecular Formula: C₆H₁₄O₆S₂

InChI: InChI=1/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3

InChIKey: InChIKey=COVZYZSDYWQREU-UHFFFAOYAO
SMILES: CS(=O)(=O)OCCCCOS(C)(=O)=O

CAS number 55-98-1

Names:
    Busulfan (JP15/USP)
    Busulfan
    busulfan
    KBio2_005648
    Myleran (TN)
    Tetramethylene bis(methanesulfonate)
    1,4-Bis(methanesulfonoxy)butane
    1,4-bis(methylsulfonyloxy)butane
    1,4-Butanediol dimethanesulfonate
    1,4-Dimesyloxybutane
    1,4-Dimethanesulfonoxybutane

Registries:
    PubChem CID 2478
    Beilstein =1791786
    CAS 55-98-1 (from NIST)
    ChEBI 28901
    Kegg D00248
    PubChem ID 11368050
    PubChem ID 7847314