PubChem Notes:

Estradiol Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. In humans, it is produced primarily by the cyclic ovaries and the PLACENTA. It is also produced by the adipose tissue of men and postmenopausal women. The 17-alpha-isomer of estradiol binds weakly to estrogen receptors (RECEPTORS, ESTROGEN) and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized.

Estradiol - definition from

[oestradiol a hormone (272 D) synthesised mainly in the ovary, but also in the placenta, testis and possibly adrenal cortex. a potent oestrogen.

Molecular Formula: C18H24O2

InChI: InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1

SMILES: [H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(O)ccc24

CAS number 50-28-2


    PubChem CID 5757
    Beilstein =1914275
    CAS 50-28-2 (from NIST)
    ChEBI 16469
    chemPDB EST
    Gmelin 290805
    Kegg C00951
    PubChem ID 12012600
    PubChem ID 4202