Nomifensine maleate

Nomifensine An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)

Molecular Formula: C₂₀H₂₂N₂O₄

InChI: InChI=1/C16H18N2.C4H4O4/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18;5-3(6)1-2-4(7)8/h2-9,14H,10-11,17H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/f/h;5,7H

InChIKey: InChIKey=GEOCVSMCLVIOEV-YQUVJEFBDI
SMILES: CN1CC(C2=C(C1)C(=CC=C2)N)C3=CC=CC=C3.C(=CC(=O)O)C(=O)O

Names:
    but-2-enedioic acid; 2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine
    HOE 984
    Nomifensine hydrogen maleate
    Nomifensine maleate
    NSC289114
    32795-47-4
    8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline maleate (1:1)
    8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-, (Z)-2-butenedioate (1:1)

Registries:
    PubChem CID 5358907
    PubChem ID 144824