Debrisoquine

PubChem Notes:

Debrisoquin An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.

Molecular Formula: C10H13N3


InChI: InChI=1/C10H13N3/c11-10(12)13-6-5-8-3-1-2-4-9(8)7-13/h1-4H,5-7H2,(H3,11,12)/f/h11H,12H2/b11-10+

InChIKey: InChIKey=JWPGJSVJDAJRLW-ZTCIKLJUDL
SMILES: C1CN(CC2=CC=CC=C21)C(=N)N

Names:
    Debrisochinum
    Debrisoquina [INN-Spanish]
    Debrisoquin
    Debrisoquine
    Debrisoquinum [INN-Latin]
    EINECS 214-470-1
    1131-64-2
    2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-
    3,4-dihydro-1H-isoquinoline-2-carboximidamide

Registries:
    PubChem CID 2966
    PubChem ID 157615