TTX

Tetrodotoxin - definition from Biology-Online.org

[(Science: protein) A potent neurotoxin (319 D) from the Japanese puffer fish. It binds to the sodium channel, blocking the passage of action potentials. Its activity closely resembles that of saxitoxin.

MediLexicon tetrodotoxin - Medical Dictionary Definition for Term 'tetrodotoxin'

[1. A potent neurotoxin found in the liver and ovaries of the Japanese pufferfish, Sphoeroides rubripes, other species of pufferfish, and some newts; produces axonal blocks of the preganglionic cholinergic fibers and the somatic motor nerves. Tetrodotoxin blocks voltage-gated Na+ channels in excitable tissues.


InChI: InChI=1/C11H17N3O8/c12-8-13-6(17)2-4-9(19,1-15)5-3(16)10(2,14-8)7(18)11(20,21-4)22-5/h2-7,15-20H,1H2,(H3,12,13,14)/t2-,3+,4-,5?,6-,7+,9+,10-,11+/m1/s1/f/h12-14H

InChIKey: InChIKey=CFMYXEVWODSLAX-OSFQBURIDD
SMILES: [H][C@@]12O[C@@]3(O)O[C@]([H])([C@]4([H])[C@@H](O)NC(=N)N[C@]4([C@H]1O)[C@@H]3O)[C@@]2(O)CO

CAS number 4368-28-9

Names:
    fugu poison
    maculotoxin
    octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol
    spheroidine
    tarichatoxin
    tetrodontoxin
    Tetrodotoxin
    tetrodotoxin
    TTX

Registries:
    PubChem CID 443368
    Beilstein =4156319
    CAS 4368-28-9 (from NIST)
    ChEBI 9506
    Kegg C11692
    PubChem ID 13857