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Pentazocine The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
[1. An opioid agonist-antagonist analgesic with some possibility for addiction but this only rarely involves withdrawal syndrome and tolerance; irritating to tissues on local injection.
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Molecular Formula:
C19H27NO
InChI: InChI=1/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18-,19-/m1/s1
InChIKey: InChIKey=VOKSWYLNZZRQPF-NIKGAXFTBY
SMILES: CC1C2CC3=C(C1(CCN2CC=C(C)C)C)C=C(C=C3)O
Names:
Fortalgesic
Fortalin
Fortral
Liticon
Pentagin
Pentazocin
pentazocine
Sosegon
Sosigon
Talwin
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Registries:
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PubChem CID 9669
PubChem ID 152882
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