Cytosine arabinoside

Cytarabine A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)

[a synthetic nucleoside used as an antimetabolite in the treatment of neoplasms. Incorrect term for arabinosylcytosine.

Molecular Formula: C₉H₁₃N₃O₅

InChI: InChI=1/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1/f/h10H2

InChIKey: InChIKey=UHDGCWIWMRVCDJ-JEMZYTBMDI
SMILES: NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O

CAS number 147-94-4

Names:
    CHEBI:28680
    cytarabine
    Cytarabine
    cytarabine
    Cytosine arabinoside
    Cytosine-1-beta-D-arabinofuranoside
    1-beta-D-Arabinofuranosylcytosine
    147-94-4
    4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
    4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
    4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

Registries:
    PubChem CID 6253
    Beilstein =89175
    CAS 147-94-4 (from NIST)
    ChEBI 28680
    Kegg C02961
    PubChem ID 11533128
    PubChem ID 5877