sulindac
PubChem Notes:
Sulindac A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.
Sulindac - definition from Biology-Online.org
[(Science: chemical) (z)-5-fluoro-2-methyl-1-((4 (methylsulfinyl)phenyl)methylene) 1h-indene-3-acetic acid. A sulfinylindene derivative whose sulfinyl moiety is converted in vivo to an active anti-inflammatory analgesic that undergoes enterohepatic circulation to maintain constant blood levels without causing gastrointestinal side effects. Pharmacological action: non-steroidal anti-inflammatory agents, cyclooxygenase inhibitors. Chemical name: 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-
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