Stylomycin

Puromycin A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.

Molecular Formula: C₂₂H₂₉N₇O₅

InChI: InChI=1/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15-,16-,18-,22-/m1/s1/f/h27H

InChIKey: InChIKey=RXWNCPJZOCPEPQ-POIFINPEDA
SMILES: CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O

Names:
    Achromycin (purine derivative)
    Achromycin
    NSC-3055
    Puromicina [INN-Spanish]
    Puromycine [INN-French]
    Puromycinum [INN-Latin]
    Puromycin [USAN:BAN:INN]
    puromycin
    Stillomycin
    Stylomycin
    (2R)-2-amino-N-[(2R,3S,4R,5R)-5-(6-dimethylaminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide

Registries:
    PubChem CID 5891
    PubChem ID 148693