SCH 23390

(R)-2,3,4,5-Tetrahydro-8-chloro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol A dopamine D1 receptor antagonist that has no effect or only very limited effect on dopamine D2 receptors. The compound has tranquilizing effects, inhibits conditioned avoidance response, impairs memory acquisition, produces dose-dependent catalepsy, blocks central serotonin receptors, and reduces the lethal effects of cocaine.

Molecular Formula: C₁₇H₁₈ClNO

InChI: InChI=1/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3

InChIKey: InChIKey=GOTMKOSCLKVOGG-UHFFFAOYAM
SMILES: CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Cl

Names:
    SCH 23390
    SCH-23390
    1H-3-Benzazepin-7-ol, 2,3,4,5-tetrahydro-8-chloro-3-methyl-5-phenyl-, (R)-
    1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-, (R)-
    2,3,4,5-Tetrahydro-8-chloro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol (R)-
    87075-17-0
    9-chloro-4-methyl-2-phenyl-4-azabicyclo[5.4.0]undeca-7,9,11-trien-10-ol

Registries:
    PubChem CID 5018
    PubChem ID 193054