Hydroxyzine pamoate

Hydroxyzine A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.

Molecular Formula: C₄₄H₄₁ClN₂O₇

InChI: InChI=1/C44H41ClN2O7/c45-33-16-14-30(15-17-33)40(29-8-2-1-3-9-29)47-20-18-46(19-21-47)22-23-53-24-25-54-44(52)39-27-32-11-5-7-13-35(32)37(42(39)49)28-36-34-12-6-4-10-31(34)26-38(41(36)48)43(50)51/h1-17,26-27,40,48-49H,18-25,28H2,(H,50,51)/f/h50H

InChIKey: InChIKey=YENRTVJWRCAGEM-VQOIMOGQCC
SMILES: C1CN(CCN1CCOCCOC(=O)C2=CC3=CC=CC=C3C(=C2O)CC4=C(C(=CC5=CC=CC=C54)C(=O)O)O)C(C6=CC=CC=C6)C7=CC=C(C=C7)Cl

Names:
    Hydroxyzine pamoate (ester)
    Hydroxyzine pamoate
    2-Naphthoic acid, 4,4'-methylenebis(3-hydroxy-, ester with 2-(2-(4-(p-chloro-alpha-phenylbenzyl)-1-piperazinyl)-ethoxy)ethanol
    2-NAPHTHOIC ACID, 4,4'-METHYLENEBIS(3-HYDROXY-, ESTER with 2-(2-(4-(p-CHLORO-alp
    4-[[3-[2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]ethoxycarbonyl]-2-hydroxy-naphthalen-1-yl]methyl]-3-hydroxy-naphthalene-2-carboxylic acid
    5978-92-7

Registries:
    PubChem CID 22287
    PubChem ID 164956