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dopamine
Dopamine - definition from Biology-Online.org
[(Science: drug) a catecholamine neurotransmitter and hormone (153 D), formed by decarboxylation of dehydroxyphenylalanine (dopa). a precursor of adrenaline and noradrenaline. pharmacologic action: 1. precursor of norepinephrine 2. stimulates dopaminergic, alpha and beta-1 adrenergic receptors: 3. dopaminergic (1-2 mcg/kg per min): cerebral, renal, and mesenteric vasodilation increase urine output 4. mixed alpha and beta-1 (2-10 mcg/kg per min): increases cardiac ouput with moderate increase systemic vascular resistance 5. Predominantly alpha (>20 mcg/kg per min): increases systemic vascular resistance Uses: 1. treat hypotension associated with bradycardia 2. stimulate cardiac output and urine output Dose: 1. start infusion at 1-5 mcg/kg per min and titrate to effect. 2. use the lowest dose that provides the desired hemodynamic improvement. 3. Do not exceed 20 mcg/kg per min. potential complications: 1. May increase pulmonary pressure and worsen pu
MediLexicon dopamine - Medical Dictionary Definition for Term 'dopamine'
[1. An intermediate in tyrosine metabolism and precursor of norepinephrine and epinephrine; neurotransmitter is the peripheral and central nervous systems; depletion of dopamine produces Parkinson disease.
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Molecular Formula:
C8H11NO2
InChI: InChI=1/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
InChIKey: InChIKey=VYFYYTLLBUKUHU-UHFFFAOYAA
SMILES: NCCc1ccc(O)c(O)c1
CAS number 51-61-6
Names:
Dopamine
dopamine
Dopamine
dopamine
KBio3_002962
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-(3,4-Dihydroxyphenyl)ethylamine
3,4-Dihydroxyphenethylamine
3,4-dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine
3-hydroxytyramine
4-(2-aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-aminoethyl)catechol
4-(2-aminoethyl)pyrocatechol
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-benzenediol
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Registries:
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PubChem CID 681
CAS 51-61-6 (from NIST)
ChEBI 18243
Kegg C03758
PubChem ID 11373057
PubChem ID 6517
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