prostacyclin

Epoprostenol A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).

Molecular Formula: C₂₀H₃₂O₅

InChI: InChI=1/C20H32O5/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24)/b11-10+,15-8u/t14-,16+,17+,18+,19-/m0/s1/f/h23H

InChIKey: InChIKey=KAQKFAOMNZTLHT-XATQXTRFDL
SMILES: CCCCCC(C=CC1C(CC2C1CC(=CCCCC(=O)O)O2)O)O

Names:
    C01312
    epoprostenol
    PGI2
    prostacyclin
    prostaglandin I2
    (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate
    35121-78-9
    5-[(1R,5S,7R,8S)-7-hydroxy-8-[(E,3S)-3-hydroxyoct-1-enyl]-4-oxabicyclo[3.3.0]oct-3-ylidene]pentanoic acid

Registries:
    PubChem CID 5280427
    PubChem ID 4527