Idrotiazide

Hydrochlorothiazide A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It has been used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.

[1. A potent orally effective diuretic and antihypertensive agent related to chlorothiazide; can cause hypokalemia and hyperglycemia.

Molecular Formula: C₇H₈ClN₃O₄S₂

InChI: InChI=1/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)/f/h9H2

InChIKey: InChIKey=JZUFKLXOESDKRF-JSGPKCTECK
SMILES: C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl

Names:
    Dichlotiazid
    Dichlotride
    Esidrix
    Hidrotiazida
    hydrochlorothiazide
    Hydrodiuretic
    Hydrosaluric
    Hypothiazide
    Hypothiazid
    Idrotiazide
    4-chloro-10,10-dioxo-10λ6-thia-7,9-diazabicyclo[4.4.0]deca-1,3,5-triene-3-sulfonamide

Registries:
    PubChem CID 3639
    PubChem ID 103995