quinidine

Quinidine An optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular action potential, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.

[1. One of the alkaloids of cinchona, a stereoisomer of quinine (the C-9 epimer); used as an antimalarial; also used in the treatment of atrial fibrillation and flutter, and paroxysmal ventricular tachycardia.

Molecular Formula: C₂₀H₂₄N₂O₂

InChI: InChI=1/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14u,19-,20-/m0/s1

InChIKey: InChIKey=LOUPRKONTZGTKE-DLVIZYDXBP
SMILES: COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O

Names:
    beta-Quinine
    CCRIS 672
    Chinidin [German]
    Conchinin
    Conquinine
    Pitayine
    Quinidine [BAN]
    quinidine
    (R)-[(5S,7R)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-(6-methoxyquinolin-4-yl)methanol
    (+)-Quinidine
    (8R,9S)-Quinidine

Registries:
    PubChem CID 5484450
    PubChem ID 148781