Temgesic

Buprenorphine A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.

Molecular Formula: C₂₉H₄₂ClNO₄

InChI: InChI=1/C29H41NO4.ClH/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28;/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3;1H/t20-,21-,24-,26+,27-,28+,29?;/m1./s1

InChIKey: InChIKey=UAIXRPCCYXNJMQ-CHLZSUIABD
SMILES: CC(C)(C)C(C)(C1CC23CCC1(C4C25CCN(C3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)O.Cl

Names:
    Buprenex
    BUPRENORPHINE HYDROCHLORIDE
    EINECS 258-396-8
    Finibron
    MR 56
    NIH 8805
    RX 6029-M
    Subutex
    Temgesic
    UM 952

Registries:
    PubChem CID 11969480
    PubChem ID 181467