furosemide

[(Science: drug) potent diuretic that increases the excretion of sodium, potassium and chloride ions and inhibits their resorption in the proximal and distal renal tubules.

[1. A loop diuretic that acts by inhibiting reabsorption of sodium and chloride in the ascending loop of Henle. Produces profound diuresis with increased excretion of calcium, magnesium, bicarbonate, ammonium, and phosphate.

Molecular Formula: C₁₂H₁₁ClN₂O₅S

InChI: InChI=1/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)/f/h16H,14H2

InChIKey: InChIKey=ZZUFCTLCJUWOSV-CDZRGBSPCX
SMILES: NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl

CAS number 54-31-9

Names:
    Frusemide
    Furosemide (JP15/USP)
    Furosemide
    furosemide
    KBioSS_001580
    Lasix (TN)
    2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid
    4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid
    4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid
    4-chloro-2-(2-furylmethylamino)-5-sulfamoyl-benzoic acid
    4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid

Registries:
    PubChem CID 3440
    CAS 54-31-9 (from NIST)
    ChEBI 5198
    Kegg D00331
    PubChem ID 11377280
    PubChem ID 7847397