trinitroglycerol

Nitroglycerin A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium.

[(Science: chemistry) A liquid appearing like a heavy oil, colourless or yellowish, and consisting of a mixture of several glycerin salts of nitric acid, and hence more properly called glycerin nitrate. It is made by the action of nitric acid on glycerin in the presence of sulphuric acid. It is extremely unstable and terribly explosive. A very dilute solution is used in medicine as a neurotic under the name of glonion. A great number of explosive compounds have been produced by mixing nitroglycerin with different substances; as, dynamite, or giant powder, nitroglycerin mixed with siliceous earth; lithofracteur, nitroglycerin with gunpowder, or with sawdust and nitrate of sodium or barium; Colonia powder, gunpowder with nitroglycerin; dualin, nitroglycerin with sawdust, or with sawdust and nitrate of potassium and some other substances; lignose, wood fibre and nitroglycerin. pharmacologic action: relaxes smooth muscle - dilates veins, dilates coronary arteries, reduces left ventricular filling pressure, lowers systemic vascular resistance, decreases myocardial oxygen demand. uses:

[1. An explosive, yellowish, oily fluid formed by the action of sulfuric and nitric acids on glycerin; used as a vasodilator, especially in angina pectoris; generates nitric oxide.

Molecular Formula: C₃H₅N₃O₉

InChI: InChI=1/C3H5N3O9/c7-4(8)13-1-3(15-6(11)12)2-14-5(9)10/h3H,1-2H2

InChIKey: InChIKey=SNIOPGDIGTZGOP-UHFFFAOYAR
SMILES: O=N(=O)OCC(CON(=O)=O)ON(=O)=O

CAS number 55-63-0

Names:
    Glycerin trinitrate
    glycerin trinitrate
    Glycerol trinitrate
    glycerol trinitrate
    glycerol, nitric acid triester
    Glyceryl trinitrate
    NG
    Nitroglycerine
    nitroglycerin
    Nitroglycerin
    nitroglycerine
    nitroglycerin
    Nitroglycerol
    nitroglycerol
    propane-1,2,3-triyl trinitrate
    Trinitroglycerin
    trinitroglycerin
    Trinitroglycerol
    trinitroglycerol
    1,2,3-propanetrioltrinitrate
    1,2,3-Propanetriyl nitrate
    1,2,3-propanetriyl nitrate
    1,3-dinitrooxypropan-2-yl nitrate

Registries:
    PubChem CID 4510
    Beilstein =1802063
    CAS 55-63-0 (from NIST)
    ChEBI 28787
    Gmelin 165859
    Kegg C07455
    PubChem ID 10318850
    PubChem ID 9658
    UM-BBD c0061