Picrotoxinum

Picrotoxin A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates.

Molecular Formula: C₃₀H₃₄O₁₃

InChI: InChI=1/C15H18O7.C15H16O6/c1-12(2,18)6-7-10(16)20-8(6)9-13(3)14(7,19)4-5-15(13,22-5)11(17)21-9;1-5(2)7-8-11(16)19-9(7)10-13(3)14(8,18)4-6-15(13,21-6)12(17)20-10/h5-9,18-19H,4H2,1-3H3;6-10,18H,1,4H2,2-3H3/t5-,6+,7u,8?,9-,13-,14-,15+;6?,7-,8u,9?,10+,13+,14+,15-/m10/s1

InChIKey: InChIKey=VJKUPQSHOVKBCO-IQTYKTTQBT
SMILES: CC(=C)C1C2C3C4(C(C1C(=O)O2)(CC5C4(O5)C(=O)O3)O)C.CC12C3C4C(C(C1(CC5C2(O5)C(=O)O3)O)C(=O)O4)C(C)(C)O

Names:
    Caswell No. 663A
    Cocculin
    Cocculus
    Fish berry
    Indian berry
    Oriental berry
    PICROTOXIN
    Picrotox
    Picrotoxine
    Picrotoxinum

Registries:
    PubChem CID 31304
    PubChem ID 173365