(5E,8E,10E,14E)-12-hydroxyicosa-5,8,10,14-tetraenoic acid

PubChem Notes:

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)

Molecular Formula: C20H32O3


InChI: InChI=1/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7+,11-8+,13-10+,17-14+/f/h22H

InChIKey: InChIKey=ZNHVWPKMFKADKW-PSNQDESJDN
SMILES: CCCCCC=CCC(C=CC=CCC=CCCCC(=O)O)O

Names:
    (5E,8E,10E,14E)-12-hydroxyicosa-5,8,10,14-tetraenoic acid
    12-Hete
    12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID
    12-R-Hete
    12-S-Hete
    12-S-Hydroxyeicosatetraenoic acid
    5,8,10,14-Eicosatetraenoic acid, 12-hydroxy-
    59985-28-3

Registries:
    PubChem CID 5353272
    PubChem ID 183592