nogalamycin

Nogalamycin An anthrocycline from a Streptomyces nogalater variant. It is a cytolytic antineoplastic that inhibits DNA-dependent RNA synthesis by binding to DNA.

Molecular Formula: C₃₉H₄₉NO₁₆

InChI: InChI=1/C39H49NO16/c1-14-32(49-7)39(4,52-10)33(50-8)36(53-14)54-19-13-37(2,48)24(34(47)51-9)15-11-16-21(27(43)20(15)19)28(44)22-18(41)12-17-30(23(22)26(16)42)55-35-29(45)25(40(5)6)31(46)38(17,3)56-35/h11-12,14,19,24-25,29,31-33,35-36,41,43,45-46,48H,13H2,1-10H3/t14u,19-,24-,25-,29-,31+,32?,33?,35-,36?,37-,38-,39u/m0/s1

InChIKey: InChIKey=KGTDRFCXGRULNK-RUQXOKOWBS
SMILES: CC1C(C(C(C(O1)OC2CC(C(C3=C2C(=C4C(=C3)C(=O)C5=C6C(=CC(=C5C4=O)O)C7(C(C(C(C(O6)O7)O)N(C)C)O)C)O)C(=O)OC)(C)O)OC)(C)OC)OC

Names:
    Antibiotic from Streptomyces nogalater
    Antibiotic 205t3
    nogalamycin
    NSC 70845
    NSC70845
    U 15167
    1404-15-5
    2, 6-Epoxy-2H-naphthaceno[1,2-b]oxocin-14-carboxylic acid, 11-[ (6-deoxy-3-C-methyl-2,3, 4-tri-O-methyl-.alpha.-L-mannopyranosyl)oxy]-4-(dimethylamino)-3, 4,5,6,9,11,12,13,14,16-decahydro-3,5,8,10,13-pentahydroxy-6, 13-dimethyl-9,16-dioxo-, methyl ester, (2.alpha.,3.beta.,4.alpha., 5.beta.,6.alpha.,11.beta.,13.alpha.,14.alpha.)-(+)-
    2, 6-Epoxy-2H-naphthaceno[1,2-b]oxocin-14-carboxylic acid, 11-[(6-deoxy-3-C-methyl-2,3, 4-tri-O-methyl-.alpha.-L-mannopyranosyl)oxy]-4-(dimethylamino)-3, 4,5,6,9.11,12,13,14,16-decahydro-3,5,8,10,13-pentahydroxy-6, 13-dimethyl-9,16-dioxo-

Registries:
    PubChem CID 250876
    PubChem ID 114031