cantharidin

Cantharidin A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.

Molecular Formula: C₁₄H₉F₃N₂O₃S

InChI: InChI=1/C14H9F3N2O3S/c15-14(16,17)9-5-6-11(19(21)22)13(7-9)23-12-4-2-1-3-10(12)18-8-20/h1-8H,(H,18,20)/f/h18H

InChIKey: InChIKey=LWVJILAVVCHCKB-GPQMBLKYCS
SMILES: C1=CC=C(C(=C1)NC=O)SC2=C(C=CC(=C2)C(F)(F)F)[N+](=O)[O-]

Names:
    cantharidin
    NSC51805
    N-[2-[2-nitro-5-(trifluoromethyl)phenyl]sulfanylphenyl]formamide
    7639-63-6

Registries:
    PubChem CID 242847
    PubChem ID 103088