indomethacin

PubChem Notes:

Indomethacin A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.

MediLexicon indomethacin - Medical Dictionary Definition for Term 'indomethacin'

[1. A potent analgesic, antipyretic, and nonsteroidal antiinflammatory agent used to treat acute exacerbations of various joint diseases. It is also used to produce closure of a patent ductus arteriosus in infants.

Molecular Formula: C20H18ClNO3


InChI: InChI=1/C20H18ClNO3/c1-12(23)10-17-13(2)22(19-9-8-16(25-3)11-18(17)19)20(24)14-4-6-15(21)7-5-14/h4-9,11H,10H2,1-3H3

InChIKey: InChIKey=ZSCHAENXWRGBMO-UHFFFAOYAH
SMILES: COc1ccc2n(c(C)c(CC(C)=O)c2c1)C(=O)c3ccc(Cl)cc3

CAS number 53-86-1

Names:
    CHEBI:5918
    Indocin (TN)
    indometacin
    Indometacin
    indomethacin
    Indomethacin
    indomethacin
    1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
    1-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]propan-2-one
    53-86-1
    [1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid

Registries:
    PubChem CID 6857419
    Beilstein =497341
    CAS 53-86-1 (from NIST)
    ChEBI 5918
    Kegg C01926
    Kegg D00141
    PubChem ID 11533297
    PubChem ID 5032