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Doxepin A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
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Molecular Formula:
C19H22ClNO
InChI: InChI=1/C19H21NO.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H
InChIKey: InChIKey=MHNSPTUQQIYJOT-UHFFFAOYAF
SMILES: CN(C)CCC=C1C2=CC=CC=C2COC3=CC=CC=C31.Cl
Names:
Doxepin hydrochloride (USP)
Doxepin Hydrochloride
D00814
Sinequan (TN)
Sinequan
1229-29-4
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Registries:
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PubChem CID 14675
PubChem ID 7847879
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