RACEMETHORPHAN

Dextromethorphan The d-isomer of the codeine analog of LEVORPHANOL. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.

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Molecular Formula: C₁₈H₂₅NO

InChI: InChI=1/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15u,17-,18-/m0/s1

InChIKey: InChIKey=MKXZASYAUGDDCJ-HOEQUUNOBL
SMILES: CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)OC

Names:
    DEA No. 9732
    EINECS 208-114-4
    Racemethorphane [INN-French]
    Racemethorphanum [INN-Latin]
    Racemethorphan [BAN:DCF:INN]
    RACEMETHORPHAN
    Racemetorfano [INN-Spanish]
    ( -)-3-Methoxy-17-methylmorphinan
    (+-)-3-Methoxy-N-methylmorphinan
    510-53-2

Registries:
    ChemSpider: InChIKey=MKXZASYAUGDDCJ-HOEQUUNOBL
    PubChem CID 5359423
    PubChem ID 153812

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