Nitroglycerin A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium.
Nitroglycerin - definition from Biology-Online.org
[(Science: chemistry) A liquid appearing like a heavy oil, colourless or yellowish, and consisting of a mixture of several glycerin salts of nitric acid, and hence more properly called glycerin nitrate. It is made by the action of nitric acid on glycerin in the presence of sulphuric acid. It is extremely unstable and terribly explosive. A very dilute solution is used in medicine as a neurotic under the name of glonion. A great number of explosive compounds have been produced by mixing nitroglycerin with different substances; as, dynamite, or giant powder, nitroglycerin mixed with siliceous earth; lithofracteur, nitroglycerin with gunpowder, or with sawdust and nitrate of sodium or barium; Colonia powder, gunpowder with nitroglycerin; dualin, nitroglycerin with sawdust, or with sawdust and nitrate of potassium and some other substances; lignose, wood fibre and nitroglycerin. pharmacologic action: relaxes smooth muscle - dilates veins, dilates coronary arteries, reduces left ventricular filling pressure, lowers systemic vascular resistance, decreases myocardial oxygen demand. uses:
MediLexicon nitroglycerin - Medical Dictionary Definition for Term 'nitroglycerin'
[1. An explosive, yellowish, oily fluid formed by the action of sulfuric and nitric acids on glycerin; used as a vasodilator, especially in angina pectoris; generates nitric oxide.
CAS number 55-63-0
glycerol, nitric acid triester
PubChem CID 4510
CAS 55-63-0 (from NIST)
PubChem ID 10318850
PubChem ID 9658